Torben Hansen
Professor
Hansen Group
Blegdamsvej 3B, Mærsk Tårnet, 8. sal
2200 København N.
Member of:
- 2005
- Published
The functional Thr130Ile and Val255Met polymorphisms of the hepatocyte nuclear factor-4alpha (HNF4A): gene associations with type 2 diabetes or altered beta-cell function among Danes
Ek, J., Rose, C. S., Jensen, D. P., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, Torben, 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 5, p. 3054-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The prevalence of the metabolic syndrome in a danish population of women with previous gestational diabetes mellitus is three-fold higher than in the general population
Lauenborg, J., Mathiesen, Elisabeth, Hansen, Torben, Glümer, C., Jørgensen, T., Borch-Johnsen, K., Hornnes, P., Pedersen, Oluf Borbye & Damm, Peter, 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 7, p. 4004-10 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation of the McKusick-Kaufman gene and studies of relationships with common forms of obesity
Andersen, K. L., Echwald, S. M., Larsen, L. H., Hamid, Y. H., Glumer, C., Jørgensen, T., Borch-Johnsen, K., Andersen, T., Sørensen, Thorkild I.A., Hansen, Torben & Pedersen, Oluf Borbye, 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 1, p. 225-230 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
Studies of the Ala/Val98 polymorphism of the hepatocyte nuclear factor-1alpha gene and the relationship to beta-cell function during an OGTT in glucose-tolerant women with and without previous gestational diabetes mellitus
Lauenborg, J., Damm, Peter, Ek, J., Glümer, C., Jørgensen, Tina, Borch-Johnsen, K., Vestergaard, H., Hornnes, P., Pedersen, Oluf Borbye & Hansen, Torben, Dec 2004, In: Diabetic Medicine. 21, 12, p. 1310-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutation analysis of suppressor of cytokine signalling 3, a candidate gene in Type 1 diabetes and insulin sensitivity
Gylvin, T., Nolsøe, R., Hansen, Torben, Nielsen, E. M. D., Bergholdt, R., Karlsen, A. E., Billestrup, Nils, Borch-Johnsen, K., Pedersen, O., Mandrup-Poulsen, Thomas, Nerup, J. & Pociot, Flemming, 1 Jul 2004, In: Diabetologia. 47, 7, p. 1273-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A common polymorphism in the promoter of the IGF-I gene associates with increased fasting serum triglyceride levels in glucose-tolerant subjects
Nielsen, E. D., Hansen, L., Lajer, M., Andersen, K. L., Echwald, S. M., Urhammer, S. A., Hansen, Torben & Pedersen, Oluf Borbye, 2004, In: Clinical Biochemistry. 37, 8, p. 660-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel syndrome of autosomal-dominant hyperinsulinemic hypoglycemia linked to a mutation in the human insulin receptor gene
Højlund, K., Hansen, Torben, Lajer, M., Henriksen, J. E., Levin, K., Lindholm, J., Pedersen, Oluf Borbye & Beck-Nielsen, H., 2004, In: Diabetes. 53, 6, p. 1592-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Grey-box modelling of pharmacokinetic/pharmacodynamic systems
Tornøe, C. W., Jacobsen, Judith Lone, Pedersen, Oluf Borbye, Hansen, Torben & Madsen, H. T., 2004, In: Journal of Pharmacokinetics and Pharmacodynamics. 31, 5, p. 401-17 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increasing incidence of diabetes after gestational diabetes: a long-term follow-up in a Danish population
Lauenborg, J., Hansen, Torben, Jensen, D. M., drb459, drb459, Mølsted-Pedersen, L., Hornnes, P., Locht, H., Pedersen, Oluf Borbye & Damm, Peter, 2004, In: Diabetes Care. 27, 5, p. 1194-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maturity-onset diabetes of the young with end-stage nephropathy: a new indication for simultaneous pancreas and kidney transplantation?
Saudek, F., Pruhová, S., Boucek, P., Lebl, J., Adamec, M., Ek, J., Pedersen, Oluf Borbye & Hansen, Torben, 2004, In: Transplantation. 77, 8, p. 1298-301 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation in the interleukin-6 receptor gene associates with type 2 diabetes in Danish whites
Hamid, Y. H., Urhammer, S. A., Jensen, D. P., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2004, In: Diabetes. 53, 12, p. 3342-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity
Frayling, T. M., Lindgren, C. M., Chevre, J. C., Menzel, S., Wishart, M., Benmezroua, Y., Brown, A., Evans, J. C., Rao, P. S., Dina, C., Lecoeur, C., Kanninen, T., Almgren, P., Bulman, M. P., Wang, Y., Mills, J., Wright-Pascoe, R., Mahtani, M. M., Prisco, F., Costa, A. & 9 others, , 2003, In: Diabetes. 52, 3, p. 872-81 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence for an association between the Leu162Val polymorphism of the PPARalpha gene and decreased fasting serum triglyceride levels in glucose tolerant subjects
Nielsen, E. D., Hansen, L., Echwald, S. M., Drivsholm, Thomas, Borch-Johnsen, K., Ekstrøm, C. T., Hansen, Torben & Pedersen, Oluf Borbye, 2003, In: Pharmacogenetics and Genomics. 13, 7, p. 417-23 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of two common polymorphisms in the PPARgamma gene on glucose tolerance and plasma insulin profiles in monozygotic and dizygotic twins: thrifty genotype, thrifty phenotype, or both?
Poulsen, P., Andersen, G., Fenger, M., Hansen, Torben, Echwald, S. M., Vølund, A., Beck-Nielsen, H., Pedersen, Oluf Borbye & Vaag, Allan, 2003, In: Diabetes. 52, 1, p. 194-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes
Nielsen, E. D., Hansen, L., Carstensen, Bendix, Echwald, S. M., Drivsholm, Thomas, Glümer, C., Thorsteinsson, B., Borch-Johnsen, K., Hansen, Torben & Pedersen, Oluf Borbye, 2003, In: Diabetes. 52, 2, p. 573-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha
Almind, K., Delahaye, L., Hansen, Torben, Van Obberghen, E., Pedersen, Oluf Borbye & Kahn, C. R., 19 Feb 2002, In: Proceedings of the National Academy of Sciences of the United States of America. 99, 4, p. 2124-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic evidence that HNF-1alpha-dependent transcriptional control of HNF-4alpha is essential for human pancreatic beta cell function
Hansen, S. K., Párrizas, M., Jensen, M. L., Pruhova, S., Ek, J., Boj, S. F., Johansen, A., Maestro, M. A., Rivera, F., Eiberg, Hans Rudolf Lytchoff, Andel, M., Lebl, J., Pedersen, Oluf Borbye, Ferrer, J. & Hansen, Torben, 2002, In: Journal of Clinical Investigation. 110, 6, p. 827-33 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Jagten på de genetiske determinanter for de formodede polygene former for type 2-diabetes. Status og perspektivering
Pedersen, Oluf Borbye, Hansen, Torben, Hansen, L., Echwald, S. M. & Urhammer, S. A., 2002, In: Ugeskrift for Laeger. 164, 16, p. 2163-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maturity-onset diabetes of the young--MODY. Molekylaergenetiske, patofysiologiske og kliniske karakteristika
Hansen, Torben, Urhammer, S. A. & Pedersen, Oluf Borbye, 2002, In: Ugeskrift for Laeger. 164, 15, p. 2017-22 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians
Rasmussen, S. K., Urhammer, S. A., Berglund, L. E., Jensen, J. N., Hansen, L., Echwald, S. M., Borch-Johnsen, K., Horikawa, Y., Mashima, H., Lithell, H., Cox, N. J., Hansen, Torben, Bell, G. I. & Pedersen, Oluf Borbye, 2002, In: Diabetes. 51, 12, p. 3561-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
- Published
Studies of the variability of the genes encoding the insulin-like growth factor I receptor and its ligand in relation to type 2 diabetes mellitus
Rasmussen, S. K., Lautier, C., Hansen, L., Echwald, S. M., Hansen, Torben, Ekstrøm, Claus Thorn, Urhammer, Søren Asger, Borch-Johnsen, K., Grigorescu, F., Smith, R. J. & Pedersen, Oluf Borbye, 1 Dec 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, 4, p. 1606-1610 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The K121Q variant of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians
Rasmussen, S. K., Urhammer, Søren Asger, Pizzuti, A., Echwald, S. M., Ekstrøm, Claus Thorn, Hansen, L., Hansen, Torben, Borch-Johnsen, K., Frittitta, L., Trischitta, V. & Pedersen, Oluf Borbye, 2000, In: Diabetes. 49, 9, p. 1608-1611 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: Evaluation of their relation with alterations in insulin secretion and insulin sensitivity
Almind, K., Frederiksen, S. K., Bernal, D., Hansen, Torben, Ambye, L., Urhammer, Søren Asger, Ekstrøm, Claus Thorn, Berglund, L., Reneland, R., Lithell, H., White, M. F., Van Obberghen, E. & Pedersen, Oluf Borbye, 11 Oct 1999, In: Diabetologia. 42, 10, p. 1244-1249 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
The Ala/Va198 polymorphism of the hepatocyte nuclear factor-1α gene contributes to the interindividual variation in serum C-peptide response during an oral glucose tolerance test: Evidence from studies of 231 glucose- tolerant first degree relatives of type 2 diabetic probands
Urhammer, Søren Asger, Hansen, Torben, Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff & Pedersen, Oluf Borbye, 1 Dec 1998, In: Journal of Clinical Endocrinology and Metabolism. 83, 12, p. 4506-4509 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of two frequent amino acid variants of the hepatocyte nuclear factor-1α gene on estimates of the pancreatic β-cell function in Caucasian glucosetolerant first-degree relatives of type 2 diabetic patients
Urhammer, Søren Asger, Møller, Ann, Nyholm, B., Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff, Clausen, J. O., Hansen, Torben, Pedersen, Oluf Borbye & Schmitz, O., 20 Nov 1998, In: Journal of Clinical Endocrinology and Metabolism. 83, 11, p. 3992-3995 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1997
- Published
Identification of a common amino acid polymorphism in the p85alpha regulatory subunit of phosphatidylinositol 3-kinase: effects on glucose disappearance constant, glucose effectiveness, and the insulin sensitivity index
Hansen, Torben, Andersen, C. B., Echwald, S. M., Urhammer, S. A., Clausen, J. O., drb459, drb459, Owens, D., Hansen, L. & Pedersen, Oluf Borbye, Mar 1997, In: Diabetes. 46, 3, p. 494-501 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1995
- Published
Identification of four amino acid substitutions in hexokinase II and studies of relationships to NIDDM, glucose effectiveness, and insulin sensitivity
Echwald, S. M., Bjørbaek, C., Hansen, Torben, Clausen, J. O., drb459, drb459, Zierath, Juleen R, Printz, R. L., Granner, D. K. & Pedersen, Oluf Borbye, Mar 1995, In: Diabetes. 44, 3, p. 347-53 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1994
- Published
Genetic variants in promoters and coding regions of the muscle glycogen synthase and the insulin-responsive GLUT4 genes in NIDDM
Bjørbaek, C., Echwald, S. M., Hubricht, P., drb459, drb459, Hansen, Torben, Zierath, Juleen R & Pedersen, Oluf Borbye, Aug 1994, In: Diabetes. 43, 8, p. 976-83 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1993
- Published
Expression of insulin receptor spliced variants and their functional correlates in muscle from patients with non-insulin-dependent diabetes mellitus
Hansen, Torben, Bjørbaek, C., drb459, drb459, Grønskov, K., Bak, J. F. & Pedersen, Oluf Borbye, Dec 1993, In: The Journal of clinical endocrinology and metabolism. 77, 6, p. 1500-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus
Almind, K., Bjørbaek, C., drb459, drb459, Hansen, Torben, Echwald, S. M. & Pedersen, Oluf Borbye, 2 Oct 1993, In: Lancet. 342, 8875, p. 828-32 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 33351878
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Estimation of allele frequency and association mapping using next-generation sequencing data
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