Fedmens genetik
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Fedmens genetik. / Echwald, Søren Morgenthaler; Larsen, Philip Just; Pedersen, Oluf Borbye; Sørensen, Thorkild I A.
In: Ugeskrift for læger, Vol. 168, No. 2, 2006, p. 150-152.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Fedmens genetik
AU - Echwald, Søren Morgenthaler
AU - Larsen, Philip Just
AU - Pedersen, Oluf Borbye
AU - Sørensen, Thorkild I A
PY - 2006
Y1 - 2006
N2 - Although environmental factors clearly play a role, studies of twins and adoptees show that obesity is a familial trait which to a large degree can be ascribed to genetic factors. According to evolutionary models, obesity-causing variants may originally have had an evolutionary benefit, whereas in a modern environment they pose a risk. Despite a clear genetic cause, the molecular genetic variations underlying common forms of obesity are not clear. Out of many hundred candidates, only a few hold up, and only variations in the MC4R gene have been found with a prevalence which may lead to common forms of obesity.
AB - Although environmental factors clearly play a role, studies of twins and adoptees show that obesity is a familial trait which to a large degree can be ascribed to genetic factors. According to evolutionary models, obesity-causing variants may originally have had an evolutionary benefit, whereas in a modern environment they pose a risk. Despite a clear genetic cause, the molecular genetic variations underlying common forms of obesity are not clear. Out of many hundred candidates, only a few hold up, and only variations in the MC4R gene have been found with a prevalence which may lead to common forms of obesity.
KW - Genetic Predisposition to Disease
KW - Humans
KW - Obesity
M3 - Tidsskriftartikel
C2 - 16403338
VL - 168
SP - 150
EP - 152
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 2
ER -
ID: 1200281