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Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994. / Jelenkovic, Aline; Hur, Yoon-Mi; Sund, Reijo; Yokoyama, Yoshie; Siribaddana, Sisira H.; Hotopf, Matthew; Sumathipala, Athula; Rijsdijk, Fruhling; Tan, Qihua; Zhang, Dongfeng; Pang, Zengchang; Aaltonen, Sari; Heikkila, Kauko; Oncel, Sevgi Y.; Aliev, Fazil; Rebato, Esther; Tarnoki, Adam D.; Tarnoki, David L.; Christensen, Kaare; Skytthe, Axel; Kyvik, Kirsten O.; Silberg, Judy L.; Eaves, Lindon J.; Maes, Hermine H.; Cutler, Tessa L.; Hopper, John L.; Ordonana, Juan R.; Sanchez-Romera, Juan F.; Colodro-Conde, Lucia; Cozen, Wendy; Hwang, Amie E.; Mack, Thomas M.; Sun, Joohon; Song, Yun-Mi; Yang, Sarah; Lee, Kayoung; Franz, Carol E.; Kremen, William S.; Lyons, Michael J.; Busjahn, Andreas; Nelson, Tracy L.; Whitfield, Keith E.; Kandler, Christian; Jang, Kerry L.; Gatz, Margaret; Butler, David A.; Stazi, Maria A.; Fagnani, Corrado; D'Ippolito, Cristina; Duncan, Glen E.; Buchwald, Dedra; Derom, Catherine A.; Vlietinck, Robert F.; Loos, Ruth J. F.; Martin, Nicholas G.; Medland, Sarah E.; Montgomery, Grant W.; Jeong, Hoe-Uk; Swan, Gary E.; Krasnow, Ruth; Magnusson, Patrik K. E.; Pedersen, Nancy L.; Dahl-Aslan, Anna K.; McAdams, Tom A.; Eley, Thalia C.; Gregory, Alice M.; Tynelius, Per; Baker, Laura A.; Tuvblad, Catherine; Bayasgalan, Gombojav; Narandalai, Danshiitsoodol; Lichtenstein, Paul; Spector, Timothy D.; Mangino, Massimo; Lachance, Genevieve; Bartels, Meike; van Beijsterveldt, Toos C. E. M.; Willemsen, Gonneke; Burt, S. Alexandra; Klump, Kelly L.; Harris, Jennifer R.; Brandt, Ingunn; Nilsen, Thomas Sevenius; Krueger, Robert F.; McGue, Matt; Pahlen, Shandell; Corley, Robin P.; Hjelmborg, Jacob v B.; Goldberg, Jack H.; Iwatani, Yoshinori; Watanabe, Mikio; Honda, Chika; Inui, Fujio; Rasmussen, Finn; Huibregtse, Brooke M.; Boomsma, Dorret I.; Sørensen, Thorkild I.A.; Kaprio, Jaakko; Silventoinen, Karri.
In:
eLife, Vol. 5, e20320, 14.12.2016, p. 1-14.
Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
Jelenkovic, A, Hur, Y-M, Sund, R, Yokoyama, Y, Siribaddana, SH, Hotopf, M, Sumathipala, A, Rijsdijk, F, Tan, Q, Zhang, D, Pang, Z, Aaltonen, S, Heikkila, K, Oncel, SY, Aliev, F, Rebato, E, Tarnoki, AD, Tarnoki, DL, Christensen, K, Skytthe, A, Kyvik, KO, Silberg, JL, Eaves, LJ, Maes, HH, Cutler, TL, Hopper, JL, Ordonana, JR, Sanchez-Romera, JF, Colodro-Conde, L, Cozen, W, Hwang, AE, Mack, TM, Sun, J, Song, Y-M, Yang, S, Lee, K, Franz, CE, Kremen, WS, Lyons, MJ, Busjahn, A, Nelson, TL, Whitfield, KE, Kandler, C, Jang, KL, Gatz, M, Butler, DA, Stazi, MA, Fagnani, C, D'Ippolito, C, Duncan, GE, Buchwald, D, Derom, CA, Vlietinck, RF, Loos, RJF, Martin, NG, Medland, SE, Montgomery, GW, Jeong, H-U, Swan, GE, Krasnow, R, Magnusson, PKE, Pedersen, NL, Dahl-Aslan, AK, McAdams, TA, Eley, TC, Gregory, AM, Tynelius, P, Baker, LA, Tuvblad, C, Bayasgalan, G, Narandalai, D, Lichtenstein, P, Spector, TD, Mangino, M, Lachance, G, Bartels, M, van Beijsterveldt, TCEM, Willemsen, G, Burt, SA, Klump, KL, Harris, JR, Brandt, I, Nilsen, TS, Krueger, RF, McGue, M, Pahlen, S, Corley, RP, Hjelmborg, JVB, Goldberg, JH, Iwatani, Y, Watanabe, M, Honda, C, Inui, F, Rasmussen, F, Huibregtse, BM, Boomsma, DI
, Sørensen, TIA, Kaprio, J & Silventoinen, K 2016, '
Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994',
eLife, vol. 5, e20320, pp. 1-14.
https://doi.org/10.7554/eLife.20320APA
Jelenkovic, A., Hur, Y-M., Sund, R., Yokoyama, Y., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Tan, Q., Zhang, D., Pang, Z., Aaltonen, S., Heikkila, K., Oncel, S. Y., Aliev, F., Rebato, E., Tarnoki, A. D., Tarnoki, D. L., Christensen, K., ... Silventoinen, K. (2016).
Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994.
eLife,
5, 1-14. [e20320].
https://doi.org/10.7554/eLife.20320Vancouver
Jelenkovic A, Hur Y-M, Sund R, Yokoyama Y, Siribaddana SH, Hotopf M et al.
Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994.
eLife. 2016 Dec 14;5:1-14. e20320.
https://doi.org/10.7554/eLife.20320Author
Jelenkovic, Aline ; Hur, Yoon-Mi ; Sund, Reijo ; Yokoyama, Yoshie ; Siribaddana, Sisira H. ; Hotopf, Matthew ; Sumathipala, Athula ; Rijsdijk, Fruhling ; Tan, Qihua ; Zhang, Dongfeng ; Pang, Zengchang ; Aaltonen, Sari ; Heikkila, Kauko ; Oncel, Sevgi Y. ; Aliev, Fazil ; Rebato, Esther ; Tarnoki, Adam D. ; Tarnoki, David L. ; Christensen, Kaare ; Skytthe, Axel ; Kyvik, Kirsten O. ; Silberg, Judy L. ; Eaves, Lindon J. ; Maes, Hermine H. ; Cutler, Tessa L. ; Hopper, John L. ; Ordonana, Juan R. ; Sanchez-Romera, Juan F. ; Colodro-Conde, Lucia ; Cozen, Wendy ; Hwang, Amie E. ; Mack, Thomas M. ; Sun, Joohon ; Song, Yun-Mi ; Yang, Sarah ; Lee, Kayoung ; Franz, Carol E. ; Kremen, William S. ; Lyons, Michael J. ; Busjahn, Andreas ; Nelson, Tracy L. ; Whitfield, Keith E. ; Kandler, Christian ; Jang, Kerry L. ; Gatz, Margaret ; Butler, David A. ; Stazi, Maria A. ; Fagnani, Corrado ; D'Ippolito, Cristina ; Duncan, Glen E. ; Buchwald, Dedra ; Derom, Catherine A. ; Vlietinck, Robert F. ; Loos, Ruth J. F. ; Martin, Nicholas G. ; Medland, Sarah E. ; Montgomery, Grant W. ; Jeong, Hoe-Uk ; Swan, Gary E. ; Krasnow, Ruth ; Magnusson, Patrik K. E. ; Pedersen, Nancy L. ; Dahl-Aslan, Anna K. ; McAdams, Tom A. ; Eley, Thalia C. ; Gregory, Alice M. ; Tynelius, Per ; Baker, Laura A. ; Tuvblad, Catherine ; Bayasgalan, Gombojav ; Narandalai, Danshiitsoodol ; Lichtenstein, Paul ; Spector, Timothy D. ; Mangino, Massimo ; Lachance, Genevieve ; Bartels, Meike ; van Beijsterveldt, Toos C. E. M. ; Willemsen, Gonneke ; Burt, S. Alexandra ; Klump, Kelly L. ; Harris, Jennifer R. ; Brandt, Ingunn ; Nilsen, Thomas Sevenius ; Krueger, Robert F. ; McGue, Matt ; Pahlen, Shandell ; Corley, Robin P. ; Hjelmborg, Jacob v B. ; Goldberg, Jack H. ; Iwatani, Yoshinori ; Watanabe, Mikio ; Honda, Chika ; Inui, Fujio ; Rasmussen, Finn ; Huibregtse, Brooke M. ; Boomsma, Dorret I. ; Sørensen, Thorkild I.A. ; Kaprio, Jaakko ; Silventoinen, Karri. / Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994. In: eLife. 2016 ; Vol. 5. pp. 1-14.
Bibtex
@article{e00322f880744ef6b5efa5be2e18744d,
title = "Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994",
abstract = "Human height variation is determined by genetic and environmental factors, but it remains unclear whether their influences differ across birth-year cohorts. We conducted an individual-based pooled analysis of 40 twin cohorts including 143,390 complete twin pairs born 1886–1994. Although genetic variance showed a generally increasing trend across the birth-year cohorts, heritability estimates (0.69-0.84 in men and 0.53-0.78 in women) did not present any clear pattern of secular changes. Comparing geographic-cultural regions (Europe, North America and Australia, and East Asia), total height variance was greatest in North America and Australia and lowest in East Asia, but no clear pattern in the heritability estimates across the birth-year cohorts emerged. Our findings do not support the hypothesis that heritability of height is lower in populations with low living standards than in affluent populations, nor that heritability of height will increase within a population as living standards improve.",
author = "Aline Jelenkovic and Yoon-Mi Hur and Reijo Sund and Yoshie Yokoyama and Siribaddana, {Sisira H.} and Matthew Hotopf and Athula Sumathipala and Fruhling Rijsdijk and Qihua Tan and Dongfeng Zhang and Zengchang Pang and Sari Aaltonen and Kauko Heikkila and Oncel, {Sevgi Y.} and Fazil Aliev and Esther Rebato and Tarnoki, {Adam D.} and Tarnoki, {David L.} and Kaare Christensen and Axel Skytthe and Kyvik, {Kirsten O.} and Silberg, {Judy L.} and Eaves, {Lindon J.} and Maes, {Hermine H.} and Cutler, {Tessa L.} and Hopper, {John L.} and Ordonana, {Juan R.} and Sanchez-Romera, {Juan F.} and Lucia Colodro-Conde and Wendy Cozen and Hwang, {Amie E.} and Mack, {Thomas M.} and Joohon Sun and Yun-Mi Song and Sarah Yang and Kayoung Lee and Franz, {Carol E.} and Kremen, {William S.} and Lyons, {Michael J.} and Andreas Busjahn and Nelson, {Tracy L.} and Whitfield, {Keith E.} and Christian Kandler and Jang, {Kerry L.} and Margaret Gatz and Butler, {David A.} and Stazi, {Maria A.} and Corrado Fagnani and Cristina D'Ippolito and Duncan, {Glen E.} and Dedra Buchwald and Derom, {Catherine A.} and Vlietinck, {Robert F.} and Loos, {Ruth J. F.} and Martin, {Nicholas G.} and Medland, {Sarah E.} and Montgomery, {Grant W.} and Hoe-Uk Jeong and Swan, {Gary E.} and Ruth Krasnow and Magnusson, {Patrik K. E.} and Pedersen, {Nancy L.} and Dahl-Aslan, {Anna K.} and McAdams, {Tom A.} and Eley, {Thalia C.} and Gregory, {Alice M.} and Per Tynelius and Baker, {Laura A.} and Catherine Tuvblad and Gombojav Bayasgalan and Danshiitsoodol Narandalai and Paul Lichtenstein and Spector, {Timothy D.} and Massimo Mangino and Genevieve Lachance and Meike Bartels and {van Beijsterveldt}, {Toos C. E. M.} and Gonneke Willemsen and Burt, {S. Alexandra} and Klump, {Kelly L.} and Harris, {Jennifer R.} and Ingunn Brandt and Nilsen, {Thomas Sevenius} and Krueger, {Robert F.} and Matt McGue and Shandell Pahlen and Corley, {Robin P.} and Hjelmborg, {Jacob v B.} and Goldberg, {Jack H.} and Yoshinori Iwatani and Mikio Watanabe and Chika Honda and Fujio Inui and Finn Rasmussen and Huibregtse, {Brooke M.} and Boomsma, {Dorret I.} and S{\o}rensen, {Thorkild I.A.} and Jaakko Kaprio and Karri Silventoinen",
year = "2016",
month = dec,
day = "14",
doi = "10.7554/eLife.20320",
language = "English",
volume = "5",
pages = "1--14",
journal = "eLife",
issn = "2050-084X",
publisher = "eLife Sciences Publications Ltd.",
}
RIS
TY - JOUR
T1 - Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994
AU - Jelenkovic, Aline
AU - Hur, Yoon-Mi
AU - Sund, Reijo
AU - Yokoyama, Yoshie
AU - Siribaddana, Sisira H.
AU - Hotopf, Matthew
AU - Sumathipala, Athula
AU - Rijsdijk, Fruhling
AU - Tan, Qihua
AU - Zhang, Dongfeng
AU - Pang, Zengchang
AU - Aaltonen, Sari
AU - Heikkila, Kauko
AU - Oncel, Sevgi Y.
AU - Aliev, Fazil
AU - Rebato, Esther
AU - Tarnoki, Adam D.
AU - Tarnoki, David L.
AU - Christensen, Kaare
AU - Skytthe, Axel
AU - Kyvik, Kirsten O.
AU - Silberg, Judy L.
AU - Eaves, Lindon J.
AU - Maes, Hermine H.
AU - Cutler, Tessa L.
AU - Hopper, John L.
AU - Ordonana, Juan R.
AU - Sanchez-Romera, Juan F.
AU - Colodro-Conde, Lucia
AU - Cozen, Wendy
AU - Hwang, Amie E.
AU - Mack, Thomas M.
AU - Sun, Joohon
AU - Song, Yun-Mi
AU - Yang, Sarah
AU - Lee, Kayoung
AU - Franz, Carol E.
AU - Kremen, William S.
AU - Lyons, Michael J.
AU - Busjahn, Andreas
AU - Nelson, Tracy L.
AU - Whitfield, Keith E.
AU - Kandler, Christian
AU - Jang, Kerry L.
AU - Gatz, Margaret
AU - Butler, David A.
AU - Stazi, Maria A.
AU - Fagnani, Corrado
AU - D'Ippolito, Cristina
AU - Duncan, Glen E.
AU - Buchwald, Dedra
AU - Derom, Catherine A.
AU - Vlietinck, Robert F.
AU - Loos, Ruth J. F.
AU - Martin, Nicholas G.
AU - Medland, Sarah E.
AU - Montgomery, Grant W.
AU - Jeong, Hoe-Uk
AU - Swan, Gary E.
AU - Krasnow, Ruth
AU - Magnusson, Patrik K. E.
AU - Pedersen, Nancy L.
AU - Dahl-Aslan, Anna K.
AU - McAdams, Tom A.
AU - Eley, Thalia C.
AU - Gregory, Alice M.
AU - Tynelius, Per
AU - Baker, Laura A.
AU - Tuvblad, Catherine
AU - Bayasgalan, Gombojav
AU - Narandalai, Danshiitsoodol
AU - Lichtenstein, Paul
AU - Spector, Timothy D.
AU - Mangino, Massimo
AU - Lachance, Genevieve
AU - Bartels, Meike
AU - van Beijsterveldt, Toos C. E. M.
AU - Willemsen, Gonneke
AU - Burt, S. Alexandra
AU - Klump, Kelly L.
AU - Harris, Jennifer R.
AU - Brandt, Ingunn
AU - Nilsen, Thomas Sevenius
AU - Krueger, Robert F.
AU - McGue, Matt
AU - Pahlen, Shandell
AU - Corley, Robin P.
AU - Hjelmborg, Jacob v B.
AU - Goldberg, Jack H.
AU - Iwatani, Yoshinori
AU - Watanabe, Mikio
AU - Honda, Chika
AU - Inui, Fujio
AU - Rasmussen, Finn
AU - Huibregtse, Brooke M.
AU - Boomsma, Dorret I.
AU - Sørensen, Thorkild I.A.
AU - Kaprio, Jaakko
AU - Silventoinen, Karri
PY - 2016/12/14
Y1 - 2016/12/14
N2 - Human height variation is determined by genetic and environmental factors, but it remains unclear whether their influences differ across birth-year cohorts. We conducted an individual-based pooled analysis of 40 twin cohorts including 143,390 complete twin pairs born 1886–1994. Although genetic variance showed a generally increasing trend across the birth-year cohorts, heritability estimates (0.69-0.84 in men and 0.53-0.78 in women) did not present any clear pattern of secular changes. Comparing geographic-cultural regions (Europe, North America and Australia, and East Asia), total height variance was greatest in North America and Australia and lowest in East Asia, but no clear pattern in the heritability estimates across the birth-year cohorts emerged. Our findings do not support the hypothesis that heritability of height is lower in populations with low living standards than in affluent populations, nor that heritability of height will increase within a population as living standards improve.
AB - Human height variation is determined by genetic and environmental factors, but it remains unclear whether their influences differ across birth-year cohorts. We conducted an individual-based pooled analysis of 40 twin cohorts including 143,390 complete twin pairs born 1886–1994. Although genetic variance showed a generally increasing trend across the birth-year cohorts, heritability estimates (0.69-0.84 in men and 0.53-0.78 in women) did not present any clear pattern of secular changes. Comparing geographic-cultural regions (Europe, North America and Australia, and East Asia), total height variance was greatest in North America and Australia and lowest in East Asia, but no clear pattern in the heritability estimates across the birth-year cohorts emerged. Our findings do not support the hypothesis that heritability of height is lower in populations with low living standards than in affluent populations, nor that heritability of height will increase within a population as living standards improve.
U2 - 10.7554/eLife.20320
DO - 10.7554/eLife.20320
M3 - Journal article
C2 - 27964777
VL - 5
SP - 1
EP - 14
JO - eLife
JF - eLife
SN - 2050-084X
M1 - e20320
ER -
