Lens fluorescence in relation to glucose tolerance and genetic predisposition to type 2 diabetes mellitus in a population-based study
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Lens fluorescence in relation to glucose tolerance and genetic predisposition to type 2 diabetes mellitus in a population-based study. / Koefoed Theil, Pernille; Kessel, Line; Hansen, Torben; Lund-Andersen, Henrik; Pedersen, Oluf; Larsen, Michael.
In: Current Eye Research, Vol. 31, No. 9, 2006, p. 733-8.Research output: Contribution to journal › Journal article › Research › peer-review
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T1 - Lens fluorescence in relation to glucose tolerance and genetic predisposition to type 2 diabetes mellitus in a population-based study
AU - Koefoed Theil, Pernille
AU - Kessel, Line
AU - Hansen, Torben
AU - Lund-Andersen, Henrik
AU - Pedersen, Oluf
AU - Larsen, Michael
PY - 2006
Y1 - 2006
N2 - The fluorescence of the lens has the characteristics of a life-long cumulative index of glycemia, and it is elevated in patients with diabetes in proportion to the duration of diabetes and the level of glycemia. Consequently, lens fluorometry should be capable of providing an estimate of prediagnostic disease duration when patients are diagnosed with type 2 diabetes. Among euglycemic subjects, first-degree relatives of patients with type 2 diabetes tend to have higher glycemia levels than subjects who are unrelated to diabetes patients. They should therefore also have the higher lens fluorescence values.
AB - The fluorescence of the lens has the characteristics of a life-long cumulative index of glycemia, and it is elevated in patients with diabetes in proportion to the duration of diabetes and the level of glycemia. Consequently, lens fluorometry should be capable of providing an estimate of prediagnostic disease duration when patients are diagnosed with type 2 diabetes. Among euglycemic subjects, first-degree relatives of patients with type 2 diabetes tend to have higher glycemia levels than subjects who are unrelated to diabetes patients. They should therefore also have the higher lens fluorescence values.
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Blood Glucose
KW - Diabetes Mellitus, Type 2
KW - Female
KW - Fluorescence
KW - Fluorophotometry
KW - Genetic Predisposition to Disease
KW - Glucose Tolerance Test
KW - Glycemic Index
KW - Humans
KW - Lens, Crystalline
KW - Male
KW - Middle Aged
U2 - 10.1080/02713680600850971
DO - 10.1080/02713680600850971
M3 - Journal article
C2 - 16966146
VL - 31
SP - 733
EP - 738
JO - Current Eye Research
JF - Current Eye Research
SN - 0271-3683
IS - 9
ER -
ID: 38336593