Maternal Distress during Pregnancy and Offspring Childhood Overweight
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Maternal Distress during Pregnancy and Offspring Childhood Overweight. / Ingstrup, Katja Glejsted; Schou Andersen, Camilla; Adeltoft, Teresa Ajslev; Pedersen, Pernille; Sørensen, Thorkild I A; Nohr, Ellen A.
In: Journal of Obesity, Vol. 2012, 2012, p. 462845.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Maternal Distress during Pregnancy and Offspring Childhood Overweight
AU - Ingstrup, Katja Glejsted
AU - Schou Andersen, Camilla
AU - Adeltoft, Teresa Ajslev
AU - Pedersen, Pernille
AU - Sørensen, Thorkild I A
AU - Nohr, Ellen A
PY - 2012
Y1 - 2012
N2 - Background. Maternal distress during pregnancy increases the intrauterine level of glucocorticoids, which may have long-term health consequences for the child. Objective. To examine if distress as a combined measure of anxiety, depression, and stress of the mother during pregnancy was associated with offspring childhood overweight at age 7. Methods. We performed a cohort study using prospective data from 37,764 women and child dyads from the Danish National Birth Cohort (1996-2002). At a telephone interview at approximately 30 weeks gestation, the women reported whether they felt anxious, depressed, or stressed. The 95 percentile for body mass index in an international reference defined childhood overweight at any given age. Logistic regression was used for the analyses. Results. The prevalence of overweight children at 7 years of age was 9.9%. Prenatal exposure to maternal distress during pregnancy was not associated with childhood overweight at 7 years of age (adjusted OR 1.06 (95% CI 0.96; 1.18)). In analyses stratified on sex, a small tendency of overweight was seen in boys (OR 1.15 (0.99; 1.33)), but not in girls (OR 0.98 (0.85; 1.13)). Conclusions. Maternal distress during pregnancy appeared to have limited, if any, influence on the risk of overweight in offspring at 7 years of age.
AB - Background. Maternal distress during pregnancy increases the intrauterine level of glucocorticoids, which may have long-term health consequences for the child. Objective. To examine if distress as a combined measure of anxiety, depression, and stress of the mother during pregnancy was associated with offspring childhood overweight at age 7. Methods. We performed a cohort study using prospective data from 37,764 women and child dyads from the Danish National Birth Cohort (1996-2002). At a telephone interview at approximately 30 weeks gestation, the women reported whether they felt anxious, depressed, or stressed. The 95 percentile for body mass index in an international reference defined childhood overweight at any given age. Logistic regression was used for the analyses. Results. The prevalence of overweight children at 7 years of age was 9.9%. Prenatal exposure to maternal distress during pregnancy was not associated with childhood overweight at 7 years of age (adjusted OR 1.06 (95% CI 0.96; 1.18)). In analyses stratified on sex, a small tendency of overweight was seen in boys (OR 1.15 (0.99; 1.33)), but not in girls (OR 0.98 (0.85; 1.13)). Conclusions. Maternal distress during pregnancy appeared to have limited, if any, influence on the risk of overweight in offspring at 7 years of age.
U2 - 10.1155/2012/462845
DO - 10.1155/2012/462845
M3 - Journal article
C2 - 22685634
VL - 2012
SP - 462845
JO - Journal of Obesity
JF - Journal of Obesity
SN - 2090-0708
ER -
ID: 48585488