Prediction of adolescent and adult adiposity outcomes from early life anthropometrics
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Prediction of adolescent and adult adiposity outcomes from early life anthropometrics. / Graversen, Lise; Sørensen, Thorkild I A; Gerds, Thomas A; Petersen, Liselotte; Sovio, Ulla; Kaakinen, Marika; Sandbaek, Annelli; Laitinen, Jaana; Taanila, Anja; Pouta, Anneli; Järvelin, Marjo-Riitta; Obel, Carsten.
In: Obesity, Vol. 23, No. 1, 01.2015, p. 162-169.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Prediction of adolescent and adult adiposity outcomes from early life anthropometrics
AU - Graversen, Lise
AU - Sørensen, Thorkild I A
AU - Gerds, Thomas A
AU - Petersen, Liselotte
AU - Sovio, Ulla
AU - Kaakinen, Marika
AU - Sandbaek, Annelli
AU - Laitinen, Jaana
AU - Taanila, Anja
AU - Pouta, Anneli
AU - Järvelin, Marjo-Riitta
AU - Obel, Carsten
N1 - © 2014 The Obesity Society.
PY - 2015/1
Y1 - 2015/1
N2 - OBJECTIVES: Maternal body mass index (BMI), birth weight, and preschool BMI may help identify children at high risk of overweight as they are (1) similarly linked to adolescent overweight at different stages of the obesity epidemic, (2) linked to adult obesity and metabolic alterations, and (3) easily obtainable in health examinations in young children. The aim was to develop early childhood prediction models of adolescent overweight, adult overweight, and adult obesity.METHODS: Prediction models at various ages in the Northern Finland Birth Cohort born in 1966 (NFBC1966) were developed. Internal validation was tested using a bootstrap design, and external validation was tested for the model predicting adolescent overweight using the Northern Finland Birth Cohort born in 1986 (NFBC1986).RESULTS: A prediction model developed in the NFBC1966 to predict adolescent overweight, applied to the NFBC1986, and aimed at labelling 10% as "at risk" on the basis of anthropometric information collected until 5 years of age showed that half of those at risk in fact did become overweight. This group constituted one-third of all who became overweight.CONCLUSIONS: Our prediction model identified a subgroup of children at very high risk of becoming overweight, which may be valuable in public health settings dealing with obesity prevention.
AB - OBJECTIVES: Maternal body mass index (BMI), birth weight, and preschool BMI may help identify children at high risk of overweight as they are (1) similarly linked to adolescent overweight at different stages of the obesity epidemic, (2) linked to adult obesity and metabolic alterations, and (3) easily obtainable in health examinations in young children. The aim was to develop early childhood prediction models of adolescent overweight, adult overweight, and adult obesity.METHODS: Prediction models at various ages in the Northern Finland Birth Cohort born in 1966 (NFBC1966) were developed. Internal validation was tested using a bootstrap design, and external validation was tested for the model predicting adolescent overweight using the Northern Finland Birth Cohort born in 1986 (NFBC1986).RESULTS: A prediction model developed in the NFBC1966 to predict adolescent overweight, applied to the NFBC1986, and aimed at labelling 10% as "at risk" on the basis of anthropometric information collected until 5 years of age showed that half of those at risk in fact did become overweight. This group constituted one-third of all who became overweight.CONCLUSIONS: Our prediction model identified a subgroup of children at very high risk of becoming overweight, which may be valuable in public health settings dealing with obesity prevention.
U2 - 10.1002/oby.20921
DO - 10.1002/oby.20921
M3 - Journal article
C2 - 25354480
VL - 23
SP - 162
EP - 169
JO - Obesity
JF - Obesity
SN - 1930-7381
IS - 1
ER -
ID: 134780869