Preschool Weight and Body Mass Index in Relation to Central Obesity and Metabolic Syndrome in Adulthood

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Preschool Weight and Body Mass Index in Relation to Central Obesity and Metabolic Syndrome in Adulthood. / Graversen, Lise; Sørensen, Thorkild I A; Petersen, Liselotte; Sovio, Ulla; Kaakinen, Marika; Sandbaek, Annelli; Laitinen, Jaana; Taanila, Anja; Pouta, Anneli; Järvelin, Marjo-Riitta; Obel, Carsten.

In: PLOS ONE, Vol. 9, No. 3, e89986, 2014, p. 1-9.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Graversen, L, Sørensen, TIA, Petersen, L, Sovio, U, Kaakinen, M, Sandbaek, A, Laitinen, J, Taanila, A, Pouta, A, Järvelin, M-R & Obel, C 2014, 'Preschool Weight and Body Mass Index in Relation to Central Obesity and Metabolic Syndrome in Adulthood', PLOS ONE, vol. 9, no. 3, e89986, pp. 1-9. https://doi.org/10.1371/journal.pone.0089986

APA

Graversen, L., Sørensen, T. I. A., Petersen, L., Sovio, U., Kaakinen, M., Sandbaek, A., Laitinen, J., Taanila, A., Pouta, A., Järvelin, M-R., & Obel, C. (2014). Preschool Weight and Body Mass Index in Relation to Central Obesity and Metabolic Syndrome in Adulthood. PLOS ONE, 9(3), 1-9. [e89986]. https://doi.org/10.1371/journal.pone.0089986

Vancouver

Graversen L, Sørensen TIA, Petersen L, Sovio U, Kaakinen M, Sandbaek A et al. Preschool Weight and Body Mass Index in Relation to Central Obesity and Metabolic Syndrome in Adulthood. PLOS ONE. 2014;9(3):1-9. e89986. https://doi.org/10.1371/journal.pone.0089986

Author

Graversen, Lise ; Sørensen, Thorkild I A ; Petersen, Liselotte ; Sovio, Ulla ; Kaakinen, Marika ; Sandbaek, Annelli ; Laitinen, Jaana ; Taanila, Anja ; Pouta, Anneli ; Järvelin, Marjo-Riitta ; Obel, Carsten. / Preschool Weight and Body Mass Index in Relation to Central Obesity and Metabolic Syndrome in Adulthood. In: PLOS ONE. 2014 ; Vol. 9, No. 3. pp. 1-9.

Bibtex

@article{46815b2166ec47ea9a268ab63efce33e,
title = "Preschool Weight and Body Mass Index in Relation to Central Obesity and Metabolic Syndrome in Adulthood",
abstract = "BACKGROUND: If preschool measures of body size routinely collected at preventive health examinations are associated with adult central obesity and metabolic syndrome, a focused use of these data for the identification of high risk children is possible. The aim of this study was to test the associations between preschool weight and body mass index (BMI) and adult BMI, central obesity and metabolic alterations.METHODS: The Northern Finland Birth Cohort 1966 (NFBC1966) (N = 4111) is a population-based cohort. Preschool weight (age 5 months and 1 year) and BMI (age 2-5 years) were studied in relation to metabolic syndrome as well as BMI, waist circumference, lipoproteins, blood pressure, and fasting glucose at the age of 31 years. Linear regression models and generalized linear regression models with log link were used.RESULTS: Throughout preschool ages, weight and BMI were significantly linearly associated with adult BMI and waist circumference. Preschool BMI was inversely associated with high-density lipoprotein levels from the age of 3 years. Compared with children in the lower half of the BMI range, the group of children with the 5% highest BMI at the age of 5 years had a relative risk of adult obesity of 6.2(95% CI:4.2-9.3), of adult central obesity of 2.4(95% CI:2.0-2.9), and of early onset adult metabolic syndrome of 2.5(95% CI:1.7-3.8).CONCLUSIONS: High preschool BMI is consistently associated with adult obesity, central obesity and early onset metabolic syndrome. Routinely collected measures of body size in preschool ages can help to identify children in need of focused prevention due to their increased risk of adverse metabolic alterations in adulthood.",
keywords = "Body Mass Index, Body Weight, Child, Preschool, Cohort Studies, Finland, Humans, Metabolic Syndrome X, Obesity",
author = "Lise Graversen and S{\o}rensen, {Thorkild I A} and Liselotte Petersen and Ulla Sovio and Marika Kaakinen and Annelli Sandbaek and Jaana Laitinen and Anja Taanila and Anneli Pouta and Marjo-Riitta J{\"a}rvelin and Carsten Obel",
year = "2014",
doi = "10.1371/journal.pone.0089986",
language = "English",
volume = "9",
pages = "1--9",
journal = "PLoS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "3",

}

RIS

TY - JOUR

T1 - Preschool Weight and Body Mass Index in Relation to Central Obesity and Metabolic Syndrome in Adulthood

AU - Graversen, Lise

AU - Sørensen, Thorkild I A

AU - Petersen, Liselotte

AU - Sovio, Ulla

AU - Kaakinen, Marika

AU - Sandbaek, Annelli

AU - Laitinen, Jaana

AU - Taanila, Anja

AU - Pouta, Anneli

AU - Järvelin, Marjo-Riitta

AU - Obel, Carsten

PY - 2014

Y1 - 2014

N2 - BACKGROUND: If preschool measures of body size routinely collected at preventive health examinations are associated with adult central obesity and metabolic syndrome, a focused use of these data for the identification of high risk children is possible. The aim of this study was to test the associations between preschool weight and body mass index (BMI) and adult BMI, central obesity and metabolic alterations.METHODS: The Northern Finland Birth Cohort 1966 (NFBC1966) (N = 4111) is a population-based cohort. Preschool weight (age 5 months and 1 year) and BMI (age 2-5 years) were studied in relation to metabolic syndrome as well as BMI, waist circumference, lipoproteins, blood pressure, and fasting glucose at the age of 31 years. Linear regression models and generalized linear regression models with log link were used.RESULTS: Throughout preschool ages, weight and BMI were significantly linearly associated with adult BMI and waist circumference. Preschool BMI was inversely associated with high-density lipoprotein levels from the age of 3 years. Compared with children in the lower half of the BMI range, the group of children with the 5% highest BMI at the age of 5 years had a relative risk of adult obesity of 6.2(95% CI:4.2-9.3), of adult central obesity of 2.4(95% CI:2.0-2.9), and of early onset adult metabolic syndrome of 2.5(95% CI:1.7-3.8).CONCLUSIONS: High preschool BMI is consistently associated with adult obesity, central obesity and early onset metabolic syndrome. Routinely collected measures of body size in preschool ages can help to identify children in need of focused prevention due to their increased risk of adverse metabolic alterations in adulthood.

AB - BACKGROUND: If preschool measures of body size routinely collected at preventive health examinations are associated with adult central obesity and metabolic syndrome, a focused use of these data for the identification of high risk children is possible. The aim of this study was to test the associations between preschool weight and body mass index (BMI) and adult BMI, central obesity and metabolic alterations.METHODS: The Northern Finland Birth Cohort 1966 (NFBC1966) (N = 4111) is a population-based cohort. Preschool weight (age 5 months and 1 year) and BMI (age 2-5 years) were studied in relation to metabolic syndrome as well as BMI, waist circumference, lipoproteins, blood pressure, and fasting glucose at the age of 31 years. Linear regression models and generalized linear regression models with log link were used.RESULTS: Throughout preschool ages, weight and BMI were significantly linearly associated with adult BMI and waist circumference. Preschool BMI was inversely associated with high-density lipoprotein levels from the age of 3 years. Compared with children in the lower half of the BMI range, the group of children with the 5% highest BMI at the age of 5 years had a relative risk of adult obesity of 6.2(95% CI:4.2-9.3), of adult central obesity of 2.4(95% CI:2.0-2.9), and of early onset adult metabolic syndrome of 2.5(95% CI:1.7-3.8).CONCLUSIONS: High preschool BMI is consistently associated with adult obesity, central obesity and early onset metabolic syndrome. Routinely collected measures of body size in preschool ages can help to identify children in need of focused prevention due to their increased risk of adverse metabolic alterations in adulthood.

KW - Body Mass Index

KW - Body Weight

KW - Child, Preschool

KW - Cohort Studies

KW - Finland

KW - Humans

KW - Metabolic Syndrome X

KW - Obesity

U2 - 10.1371/journal.pone.0089986

DO - 10.1371/journal.pone.0089986

M3 - Journal article

C2 - 24595022

VL - 9

SP - 1

EP - 9

JO - PLoS ONE

JF - PLoS ONE

SN - 1932-6203

IS - 3

M1 - e89986

ER -

ID: 137511717