Kei Sakamoto
Professor
Sakamoto Group
Blegdamsvej 3B, Mærsk Tårnet, 6. sal, 2200 København N.
Member of:
- Published
In Vitro Screening for Probiotic Properties of Lactobacillus and Bifidobacterium Strains in Assays Relevant for Non-Alcoholic Fatty Liver Disease Prevention
Lopez-Escalera, S., Lund, M. L., Hermes, G. D. A., Choi, Beatrice So-Yun, Sakamoto, Kei & Wellejus, A., 2023, In: Nutrients. 15, 10, 23 p., 2361.Research output: Contribution to journal › Journal article › Research › peer-review
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Skeletal muscle
Markby, G. R. & Sakamoto, Kei, 1 Jan 2021, Autophagy in Health and Disease. Elsevier, p. 213-225 13 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Transcription factor EB and TFE3: new metabolic coordinators mediating adaptive responses to exercise in skeletal muscle?
Markby, G. R. & Sakamoto, Kei, 2020, In: American Journal of Physiology: Endocrinology and Metabolism. 319, 4, p. E763-E768 6 p.Research output: Contribution to journal › Review › Research › peer-review
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Mechanism of glycogen synthase inactivation and interaction with glycogenin
Marr, L., Biswas, Dipsikha, Daly, L. A., Browning, C., Vial, S. C. M., Maskell, D. P., Hudson, C., Bertrand, J. A., Pollard, J., Ranson, N. A., Khatter, H., Eyers, C. E., Sakamoto, Kei & Zeqiraj, E., 2022, In: Nature Communications. 13, 1, 14 p., 3372.Research output: Contribution to journal › Journal article › Research › peer-review
MiR-184 expression is regulated by AMPK in pancreatic islets
Martinez-Sanchez, A., Nguyen-Tu, M. S., Cebola, I., Yavari, A., Marchetti, P., Piemonti, L., De Koning, E., Shapiro, A. M. J., Johnson, P., Sakamoto, Kei, Smith, D. M., Leclerc, I., Ashrafian, H., Ferrer, J. & Rutter, G. A., May 2018, In: FASEB Journal. 32, 5, p. 2587-2600 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Reduced expression of the murine p85α subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes
Mauvais-Jarvis, F., Ueki, K., Fruman, D. A., Hirshman, M. F., Sakamoto, Kei, Goodyear, L. J., Iannacone, M., Accili, D., Cantley, L. C. & Ronald Kahn, C., 1 Jan 2002, In: Journal of Clinical Investigation. 109, 1, p. 141-149 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis
McManus, E. J., Sakamoto, Kei, Armit, L. J., Ronaldson, L., Shpiro, N., Marquez, R. & Alessi, D. R., 20 Apr 2005, In: EMBO Journal. 24, 8, p. 1571-1583 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Dual regulation of glycogen synthase kinase 3 (GSK3)α/β by protein kinase C (PKC)α and Akt promotes thrombin-mediated integrin α∥bβ3 activation and granule secretion in platelets
Moore, S. F., Van Den Bosch, M. T. J., Hunter, R. W., Sakamoto, Kei, Poole, A. W. & Hers, I., 8 Feb 2013, In: Journal of Biological Chemistry. 288, 6, p. 3918-3928 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Role of the PDK1-PKB-GSK3 pathway in regulating glycogen synthase and glucose uptake in the heart
Mora, A., Sakamoto, Kei, McManus, E. J. & Alessi, D. R., 27 Jul 2005, In: FEBS Letters. 579, 17, p. 3632-3638 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function
Mottillo, E. P., Desjardins, E. M., Crane, J. D., Smith, B. K., Green, A. E., Ducommun, S., Henriksen, T. I., Rebalka, I. A., Razi, A., Sakamoto, Kei, Schéele, Camilla Charlotte Nielsen, Kemp, B. E., Hawke, T. J., Ortega, J., Granneman, J. G. & Steinberg, G. R., 12 Jul 2016, In: Cell Metabolism. 24, 1, p. 118-129 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration
Mounier, R., Théret, M., Arnold, L., Cuvellier, S., Bultot, L., Göransson, O., Sanz, N., Ferry, A., Sakamoto, Kei, Foretz, M., Viollet, B. & Chazaud, B., 6 Aug 2013, In: Cell Metabolism. 18, 2, p. 251-264 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Important role for AMPKα1 in limiting skeletal muscle cell hypertrophy
Mounier, R., Lantier, L., Leclerc, J., Sotiropoulos, A., Pende, M., Daegelen, D., Sakamoto, Kei, Foretz, M. & Viollet, B., Jul 2009, In: FASEB Journal. 23, 7, p. 2264-2273 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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CaMKK2 is not involved in contraction-stimulated AMPK activation and glucose uptake in skeletal muscle
Negoita, F., Addinsall, A. B., Hellberg, K., Bringas, C. F., Hafen, P. S., Sermersheim, T. J., Agerholm, M., Lewis, C. T. A., Ahwazi, D., Ling, N. X. Y., Larsen, J. K., Deshmukh, A. S., Hossain, M. A., Oakhill, J. S., Ochala, J., Brault, J. J., Sankar, U., Drewry, D. H., Scott, J. W., Witczak, C. A. & 1 others, , 2023, In: Molecular Metabolism. 75, 14 p., 101761.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis
Neopane, K., Kozlov, N., Negoita, F., Murray-Segal, L., Brink, R., Hoque, A., Ovens, A. J., Tjin, G., McAloon, L. M., Yu, D., Ling, N. X. Y., Sanders, M. J., Oakhill, J. S., Scott, J. W., Steinberg, G. R., Loh, K., Kemp, B. E., Sakamoto, Kei & Galic, S., 2022, In: Cell Reports. 41, 12, 26 p., 111862.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase
Nguyen-Tu, M., Harris, J., Martinez-Sanchez, A., Chabosseau, P., Hu, M., Georgiadou, E., Pollard, A., Otero, P., Lopez-Noriega, L., Leclerc, I., Sakamoto, Kei, Schmoll, D., Smith, D. M., Carling, D. & Rutter, G. A., 2022, In: Diabetologia. 65, p. 997-1011 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
How long does the protective effect on eccentric exercise-induced muscle damage last?
Nosaka, K., Sakamoto, Kei, Newton, M. & Sacco, P., 1 Jan 2001, In: Medicine and Science in Sports and Exercise. 33, 9, p. 1490-1495 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
The repeated bout effect of reduced-load eccentric exercise on elbow flexor muscle damage
Nosaka, K., Sakamoto, Kei, Newton, M. & Sacco, P., 1 Jan 2001, In: European Journal of Applied Physiology. 85, 1-2, p. 34-40 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Changes in plasma enzyme activity after intramuscular injection of bupivacaine into the human biceps brachii
Nosaka, K. & Sakamoto, Kei, 1 Dec 1999, In: Acta Physiologica Scandinavica. 167, 3, p. 259-265 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Effect of elbow joint angle on the magnitude of muscle damage to the elbow flexors
Nosaka, K. & Sakamoto, Kei, 1 Jan 2001, In: Medicine and Science in Sports and Exercise. 33, 1, p. 22-29 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Changes in Leukocytes after Eccentric Exerclse ot the Elbow Flexors
Nosaka, K. & Sakamoto, Kei, 25 May 2000, In: Advances in Exercise and Sports Physiology. 6, 2, p. 59-65 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Influence of Arm-cranking on Changes in Plasma CK Activity after High Force Eccentric Exercise of the Elbow Flexors
Nosaka, K., Sakamoto, Kei & Newton, M., 25 Mar 2002, In: Advances in Exercise and Sports Physiology. 8, 2, p. 45-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Influence of pre-exercise muscle temperature on responses to eccentric exercise
Nosaka, K., Sakamoto, Kei, Newton, M. & Sacco, P., 1 Apr 2004, In: Journal of Athletic Training. 39, 2, p. 132-137 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
The Ca2+/calmodulin-dependent kinase kinase β-AMP-activated protein kinase-α1 pathway regulates phosphorylation of cytoskeletal targets in thrombin-stimulated human platelets
Onselaer, M. B., Oury, C., Hunter, R. W., Eeckhoudt, S., Barile, N., Lecut, C., Morel, N., Viollet, B., Jacquet, L. M., Bertrand, L., Sakamoto, Kei, Vanoverschelde, J. L., Beauloye, C. & Horman, S., Jun 2014, In: Journal of Thrombosis and Haemostasis. 12, 6, p. 973-986 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver
Patel, K., Foretz, M., Marion, A., Campbell, D. G., Gourlay, R., Boudaba, N., Tournier, E., Titchenell, P., Peggie, M., Deak, M., Wan, M., Kaestner, K. H., Göransson, O., Viollet, B., Gray, N. S., Birnbaum, M. J., Sutherland, C. & Sakamoto, Kei, 4 Aug 2014, In: Nature Communications. 5, 4535.Research output: Contribution to journal › Journal article › Research › peer-review
Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism
Patra, K. C., Kato, Y., Mizukami, Y., Widholz, S., Boukhali, M., Revenco, I., Grossman, E. A., Ji, F., Sadreyev, R. I., Liss, A. S., Screaton, R. A., Sakamoto, Kei, Ryan, D. P., Mino-Kenudson, M., Castillo, C. F. D., Nomura, D. K., Haas, W. & Bardeesy, N., 1 Jul 2018, In: Nature Cell Biology. 20, 7, p. 811-822 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 227976158
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Exercise-induced molecular mechanisms promoting glycogen supercompensation in human skeletal muscle
Research output: Contribution to journal › Journal article › Research › peer-review
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182
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Chemical genetic screen identifies Gapex-5/GAPVD1 and STBD1 as novel AMPK substrates
Research output: Contribution to journal › Journal article › Research › peer-review
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Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle
Research output: Contribution to journal › Journal article › Research › peer-review
Published