Enteroendocrine cell types revisited

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Enteroendocrine cell types revisited. / Engelstoft, Maja S; Egerod, Kristoffer Lihme; Lund, Mari L; Schwartz, Thue W.

In: Current Opinion in Pharmacology, Vol. 13, No. 6, 12.2013, p. 912-21.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Engelstoft, MS, Egerod, KL, Lund, ML & Schwartz, TW 2013, 'Enteroendocrine cell types revisited', Current Opinion in Pharmacology, vol. 13, no. 6, pp. 912-21. https://doi.org/10.1016/j.coph.2013.09.018

APA

Engelstoft, M. S., Egerod, K. L., Lund, M. L., & Schwartz, T. W. (2013). Enteroendocrine cell types revisited. Current Opinion in Pharmacology, 13(6), 912-21. https://doi.org/10.1016/j.coph.2013.09.018

Vancouver

Engelstoft MS, Egerod KL, Lund ML, Schwartz TW. Enteroendocrine cell types revisited. Current Opinion in Pharmacology. 2013 Dec;13(6):912-21. https://doi.org/10.1016/j.coph.2013.09.018

Author

Engelstoft, Maja S ; Egerod, Kristoffer Lihme ; Lund, Mari L ; Schwartz, Thue W. / Enteroendocrine cell types revisited. In: Current Opinion in Pharmacology. 2013 ; Vol. 13, No. 6. pp. 912-21.

Bibtex

@article{5cc4f08a5dbe4b9480516aef5ac55644,
title = "Enteroendocrine cell types revisited",
abstract = "The GI-tract is profoundly involved in the control of metabolism through peptide hormones secreted from enteroendocrine cells scattered throughout the gut mucosa. A large number of recently generated transgenic reporter mice have allowed for direct characterization of biochemical and cell biological properties of these previously highly elusive enteroendocrine cells. In particular the surprisingly broad co-expression of six functionally related hormones in the intestinal enteroendocrine cells indicates that it should be possible to control not only the hormone secretion but also the type and number of enteroendocrine cells. However, this will require a more deep understanding of the factors controlling differentiation, gene expression and specification of the enteroendocrine cells during their weekly renewal from progenitor cells in the crypts of the mucosa.",
keywords = "Animals, Enteroendocrine Cells, Gastrointestinal Hormones, Humans, Intestinal Mucosa, Intestines",
author = "Engelstoft, {Maja S} and Egerod, {Kristoffer Lihme} and Lund, {Mari L} and Schwartz, {Thue W}",
note = "Copyright {\textcopyright} 2013 Elsevier Ltd. All rights reserved.",
year = "2013",
month = dec,
doi = "10.1016/j.coph.2013.09.018",
language = "English",
volume = "13",
pages = "912--21",
journal = "Current Opinion in Pharmacology",
issn = "1471-4892",
publisher = "Elsevier Ltd. * Current Opinion Journals",
number = "6",

}

RIS

TY - JOUR

T1 - Enteroendocrine cell types revisited

AU - Engelstoft, Maja S

AU - Egerod, Kristoffer Lihme

AU - Lund, Mari L

AU - Schwartz, Thue W

N1 - Copyright © 2013 Elsevier Ltd. All rights reserved.

PY - 2013/12

Y1 - 2013/12

N2 - The GI-tract is profoundly involved in the control of metabolism through peptide hormones secreted from enteroendocrine cells scattered throughout the gut mucosa. A large number of recently generated transgenic reporter mice have allowed for direct characterization of biochemical and cell biological properties of these previously highly elusive enteroendocrine cells. In particular the surprisingly broad co-expression of six functionally related hormones in the intestinal enteroendocrine cells indicates that it should be possible to control not only the hormone secretion but also the type and number of enteroendocrine cells. However, this will require a more deep understanding of the factors controlling differentiation, gene expression and specification of the enteroendocrine cells during their weekly renewal from progenitor cells in the crypts of the mucosa.

AB - The GI-tract is profoundly involved in the control of metabolism through peptide hormones secreted from enteroendocrine cells scattered throughout the gut mucosa. A large number of recently generated transgenic reporter mice have allowed for direct characterization of biochemical and cell biological properties of these previously highly elusive enteroendocrine cells. In particular the surprisingly broad co-expression of six functionally related hormones in the intestinal enteroendocrine cells indicates that it should be possible to control not only the hormone secretion but also the type and number of enteroendocrine cells. However, this will require a more deep understanding of the factors controlling differentiation, gene expression and specification of the enteroendocrine cells during their weekly renewal from progenitor cells in the crypts of the mucosa.

KW - Animals

KW - Enteroendocrine Cells

KW - Gastrointestinal Hormones

KW - Humans

KW - Intestinal Mucosa

KW - Intestines

U2 - 10.1016/j.coph.2013.09.018

DO - 10.1016/j.coph.2013.09.018

M3 - Journal article

C2 - 24140256

VL - 13

SP - 912

EP - 921

JO - Current Opinion in Pharmacology

JF - Current Opinion in Pharmacology

SN - 1471-4892

IS - 6

ER -

ID: 117973306